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Table of contents:
This revised text contains 21 chapters co-authored by five molecular biologists and provides authoritative coverage of a fast-changing discipline. Included is balanced coverage of prokaryotic and eukaryotic systems and information on important experiments and techniques.
Contents:
Part I Chemistry and genetics: the Mendelian view of the world
- nucleic acids convey genetic information
- the importance of weak chemical interactions
- the importance of high energy bonds
- weak and strong bonds determine macromolecular interactions
Part II Central dogma: the structures of DNA and RNA
- chromatin and the nucleosome
- the replication of DNA
- the mutability and repair of DNA
- site specific recombination and transposition of DNA
- mechanisms of transcription
- the processing of RNA
- translation
- the genetic code
Part III Regulation: gene regulation in prokaryotes
- gene regulation in eukaryotes
- gene regulation in development
- comparative genomics and the evolution of animal diversity
Part IV Methods: techniques of molecular biology
- model systems - cells and viruses.
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